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13th June 2024  Content supplied by: AMSBIO

How AMSBIO Can Support Your Cultured Meat Research and Improve Manufacturing Methods.


AMSBIO offers a range of kits, media, and reagents that enable the development of food in a way that is not wasteful of natural resources and is not detrimental to the environment or consumer health.

Recent advances in biotechnological methods have enabled the development of cultured meat - meat grown in a laboratory using stem cell technology that mimics the texture, flavor, and nutritional value of conventional meat. Cultured meat has the potential to be less resource intensive through the lessening of animal husbandry and slaughter, leading to knock-on effects such as decreasing air pollution, decreasing deforestation, reducing water use/contamination, slowing biodiversity loss, shrinking antibiotic resistance, and lessening foodborne illnesses.

Products for cultured meat research and development from AMSBIO fall broadly into three areas.

  • Products to create the correct environment and stimuli for cultured cells
  • Standards and kits to test if these cells are behaving like the in vivo model
  • Cryopreservation media to archive cells for reference or future use

The company’s growing range of high-quality products for pioneering cultured meat research includes skeletal muscle differentiation kits, recombinant extracellular matrices, 3D scaffolds, and cryopreservation media.

The manufacturing of cultured meat requires a suitable source of cells that can differentiate into muscle and fat cells. A 2023 study by Kalkehi and co-workers discussed the implications of using primary cells which required the repeated harvest of cells from different animal sources. This challenge was overcome by successful cryopreservation of bovine myogenic cells in CELLBANKER® media available from AMSBIO, which maintained cell quality for downstream production of cultured meat products.

Another vital component in the development of new cell-based foods is the culture media and matrix, which support cell growth and differentiation. In 2022, Takahashi and colleagues demonstrated the efficiency of iMatrix-511 Laminin E8 fragments, available from AMSBIO, for the adherence of bovine myogenic cells extracted from bovine meat and their differentiation into myotubes. These micropatterned culture substrates were used to form a scaffold upon which myotubes could then be aligned into myofibers that mimic the structure of native muscle tissue.

Currently, research is underway to decipher the optimal combination of cellular source, growth media, bioprocesses, and biomaterials to successfully scale up processing of cultured meat products to a commercial level. Offered as a product to consumers, all materials and procedures used in cultured meat production must follow strict regulations under GMP and FDA approval to make sure the end product is safe for consumption.

The major challenge faced in manufacturing is the high cost of large-scale production. Therefore, to reduce costs in the future, procedures and automated processes must be standardized. AMSBIO is aiming to ease the transition from bench-scale to manufacturing with a range of GMP-compliant products and services.

Read the blog ‘Cultured Meat: from cell culture to restaurant table’

Learn More or use the "Request Information" button below to connect with AMSBIO.


    

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Date Published: 13th June 2024

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